QM-FN-SO3

Tocris Bioscience | Catalog # 7958

Blood-brain barrier penetrant, NIR aggregation-induced emission active probe of amyloid β plaques. Used for: in vitro, in situ and in vivo imaging of amyloid β plaques. Application: confocal microscopy and in vivo imaging
Tocris Bioscience
Discontinued Product
7958 has been discontinued. View all Fluorescent Probes products.

Key Product Details

Description

Blood-brain barrier penetrant, NIR aggregation-induced emission active probe of amyloid β plaques. Used for: in vitro, in situ and in vivo imaging of amyloid β plaques. Application: confocal microscopy and in vivo imaging

Wavelength

Excitation = 488 nm, Emission = 680 nm
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Product Description

Key information: QM-FN-SO3 is a near-infrared (NIR) aggregation-induced emission active probe for in vivo imaging of amyloid β (Aβ) plaques. Blood brain barrier penetrant.

Used for: detection of Aβ plaques in vitro, in situ and in vivo.

Application: confocal microscopy and in vivo imaging.

Properties and Photophysical Data: QM-FN-SO3 shows high binding affinity, ultra-high sensitivity, low signal-to-noise ratio, and large stokes shift (170 nm) reducing excitation light-induced self-quenching. Excitation and emission maxima (λ) are 488 nm and 680 nm, respectively.

Optical Data

QM-FN-SO3 Dye Spectra
λabs 488 nm
λem 680 nm
Cell Permeable Yes
Application Confocal imaging of amyloid-beta plaques, in vitro and in vivo

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Product Specifications for QM-FN-SO3

Molecular Weight

564.65

Formula

C29H25N4O3S2.Na

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

Sodium 3-(4-(Dicyanomethylene)-2-(2-(5-(4-(dimethylamino)phenyl)thiophen-2-yl)vinyl)quinolin-1(4H)-yl)propane-1-sulfonate

CAS Number

2316820-94-5

PubChem ID

154727758

InChI Key

WYMGXQAGHDNQOV-UEIGIMKUSA-M

SMILES

CN(C)C1=CC=C(C=C1)C2=CC=C(S2)/C=C/C(N(CCCS(=O)([O-])=O)C3=C/4C=CC=C3)=CC4=C(C#N)/C#N.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 11.29 20
DMSO 28.23 50

Preparing Stock Solutions for QM-FN-SO3

The following data is based on the product molecular weight 564.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.54 mL 17.71 mL 35.42 mL
2.5 mM 0.71 mL 3.54 mL 7.08 mL
5 mM 0.35 mL 1.77 mL 3.54 mL
25 mM 0.07 mL 0.35 mL 0.71 mL

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Product Documents for QM-FN-SO3

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for QM-FN-SO3

For research use only

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