RAP1GAP Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-83002

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all RAP1GAP Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RAP1GAP Antibody - BSA Free

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002] - Staining of mouse hippocampus shows cytoplasmic positivity in a subset of interneurons in the CA1 area.
Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002] - Staining of human kidney shows strong positivity in distal tubules and Bowman's capsule.
Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002] - Staining of human hippocampus shows cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002] - Staining of human cerebral cortex shows cytoplasmic immunoreactivity in neuronal cell bodies.
Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry-Paraffin: RAP1GAP Antibody [NBP1-83002] - Staining of human cerebellum shows strong cytoplasmic immunoreactivity in Purkinje cells and neurons in the molecular layer.
Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002] - Staining of mouse midbrain shows strong immunoreactivity in locus coeruleus neurons.
Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002] - Staining of mouse cingulate cortex shows strong cytoplasmic positivity in neuronal cell bodies and proximal dendrites.
Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002] - Staining of mouse hypothalamus shows positivity in neuronal cell bodies and processes in the lateral preoptic area.
Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002]

Immunohistochemistry: RAP1GAP Antibody [NBP1-83002] - Staining of mouse globus pallidus shows strong cytoplasmic immunoreactivity in neurons.

Applications for RAP1GAP Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAP1GAP

Rap1GAP, an 85/95kDa protein, is a member of a family of GAP's specific for Rap1 (1). Though to be an important tumor suppressor, Rap1GAP has no sequence homology with other GAPs such as RasGAP, RanGAP and RhoGAP. Purified as a cytosolic and membrane-bound protein, both isoforms consist of two monomers each contain a dimerization and a catalytic domain (2-4). Mutations in the GAP domain of the tumor suppressor tuberin, can cause benign tumor phenotype tuberous sclerosis (5).

Alternate Names

GTPase activating protein 1, RAP1 GTPase activating protein

Gene Symbol

RAP1GAP

Additional RAP1GAP Products

Product Documents for RAP1GAP Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for RAP1GAP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for RAP1GAP Antibody - BSA Free

Customer Reviews for RAP1GAP Antibody - BSA Free

There are currently no reviews for this product. Be the first to review RAP1GAP Antibody - BSA Free and earn rewards!

Have you used RAP1GAP Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies