Rec 15/2615 dihydrochloride

Key Product Details

Product Description

Rec 15/2615 dihydrochloride is a selective α_1B-adrenoceptor antagonist (K_i values are 0.3, 1.9 and 2.6 nM at human α_1B, α_1A and α_1D receptors respectively).

Product Specifications for Rec 15/2615 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Rec 15/2615 dihydrochloride

The following data is based on the product molecular weight 568.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.76 mL	8.80 mL	17.59 mL
5 mM	0.35 mL	1.76 mL	3.52 mL
10 mM	0.18 mL	0.88 mL	1.76 mL
50 mM	0.04 mL	0.18 mL	0.35 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Bremner Ligand design for α₁ adrenoceptor subtype selective antagonist. Bioorg.Med.Chem. 2000 PMID: 10968279
• Morston α_1A-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br.J.Pharmacol. 2007 PMID: 17115072
• Testa Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): Role of the alpha-1L adrenoceptor in tissue selectivity, part II. J.Pharmacol.Exp.Ther. 1997 PMID: 9190864

Product Documents for Rec 15/2615 dihydrochloride