Catalog Number: 5193
Chemical Name: 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile
Biological Activity
N-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.
Technical Data
  • M.Wt:
    282.36
  • Formula:
    C15H14N4S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    949912-58-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Chemical inhibition of NAT10 corrects defects of laminopathic cells.
    Larrieu et al.
    Science, 2014;344:527

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