Rifampicin

Tocris Bioscience | Catalog # 4121

Pregnane X receptor agonist; antibiotic
Tocris Bioscience
Discontinued Product
4121 has been discontinued. View all Pregnane X Receptor Activators products.

Key Product Details

Description

Pregnane X receptor agonist; antibiotic

Alternative Names

Rifampin
View all Pregnane X Receptor Activators »

Product Description

Rifampicin is an antibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR).

Product Specifications for Rifampicin

Molecular Weight

822.94

Formula

C43H58N4O12

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3-[[(4-Methyl-1-piperazinyl)imino]methyl]-rifamycin

CAS Number

13292-46-1

PubChem ID

5381226

InChI Key

FZYOVNIOYYPUPY-ZTWDQPHTSA-N

SMILES

CN(CC1)CCN1/N=C/C2=C(O)C3=C(C4=O)C5=C(C)C(O)=C3C(O)=C2NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@H]([C@H]([C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)/C=C/O[C@@]4(C)O5)O)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 82.29 100

Preparing Stock Solutions for Rifampicin

The following data is based on the product molecular weight 822.94.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.22 mL 6.08 mL 12.15 mL
5 mM 0.24 mL 1.22 mL 2.43 mL
10 mM 0.12 mL 0.61 mL 1.22 mL
50 mM 0.02 mL 0.12 mL 0.24 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Rifampicin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rifampicin

For research use only

⚠ WARNING: This product can expose you to chemicals including Rifampin, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Customer Reviews for Rifampicin (1)

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  • Rifampicin resisistance in E.coli cells was studied
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 12/03/2018
    In our lab rifampicin resisistance in E.coli cells was studied.To assess the level of antibiotic resistance, the minimum inhibitory concentration (MICs) of rifampicin in the non-mutated strain and mutated strain were compared.
    Rifampicin 4121

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