Catalog Number: 2005
Chemical Name: 1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinol hydrochloride
Biological Activity
Selective antagonist for NR2B-containing NMDA receptors (Ki = 31 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 15 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. In vitro binding properties in rat brain of [3H] Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits.
    Mutel et al.
    J.Neurochem., 1998;70:214
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