Ro 04-5595 hydrochloride

Catalog # Availability Size / Price Qty
Ro 04-5595 hydrochloride | CAS No. 64047-73-0 | NMDA Receptor Antagonists
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Description: GluN2B-selective NMDA antagonist

Chemical Name: 1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinol hydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Ro 04-5595 hydrochloride is a selective antagonist for GluN2B (formally NR2B) containing NMDA receptors (Ki = 31 nM).

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data

Soluble to 15 mM in water and to 100 mM in DMSO
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. In vitro binding properties in rat brain of [3H] Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits.
    Mutel et al.
    J.Neurochem., 1998;70:214

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Citation for Ro 04-5595 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Ro 04-5595 hydrochloride include:

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