Ro 67-7476

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Ro 67-7476 | CAS No. 298690-60-5 | Group I mGluR Modulators
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Description: Positive allosteric modulator of mGlu1 receptors

Chemical Name: (2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine

Purity: ≥99%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

Positive allosteric modulator of mGlu1 receptors. Potentiates glutamate-induced calcium release (EC50 = 60.1 nM at rat mGluR1a). Displays no activity at human mGlu1 receptors.

Technical Data

M.Wt:
319.39
Formula:
C17H18FNO2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
298690-60-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Ro 67-7476

The citations listed below are publications that use Tocris products. Selected citations for Ro 67-7476 include:

1 Citation: Showing 1 - 1

  1. SHANK3 controls maturation of social reward circuits in the VTA.
    Authors: Bariselli Et al.
    Nat Neurosci  2016;19:926

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