Roxindole hydrochloride

Catalog # Availability Size / Price Qty
1559/10
1559/50
Roxindole hydrochloride | CAS No. 108050-82-4 | Non-selective Dopamine Receptor Agonists
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Description: Dopamine D2 autoreceptor agonist. Also has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter
Alternative Names: EMD 49980

Chemical Name: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-ol hydrochloride

Purity: ≥98%

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Biological Activity

Dopamine D2 autoreceptor agonist, with affinity for D3, D4 and 5-HT1 receptors (pKi values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D2, D3, D4, 5-HT1A, 5-HT1B and 5-HT1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo.

Technical Data

M.Wt:
382.93
Formula:
C23H26N2O.HCl
Solubility:
Soluble to 50 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Desiccate at -20°C
CAS No:
108050-82-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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