Chemical Name: Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2+) dichloride
Biological ActivityRuBi-Nicotine is a ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A caged nicotine with nanosecond range kinetics and visible light sensitivity.
Filevich et al.
Citation for RuBi-Nicotine
The citations listed below are publications that use Tocris products. Selected citations for RuBi-Nicotine include:
1 Citation: Showing 1 - 1
Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections.
Authors: Lorna W Et al.
Front Neural Circuits 2022;16:978837
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