(S)-(-)-Pindolol

Key Product Details

Product Description

(S)-(-)-Pindolol is a 5-HT_1A/1B receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β₃-adrenoceptors. More active enantiomer of pindolol.

Racemate also available.

Product Specifications for (S)-(-)-Pindolol

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (S)-(-)-Pindolol

The following data is based on the product molecular weight 248.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.03 mL	20.14 mL	40.27 mL
5 mM	0.81 mL	4.03 mL	8.05 mL
10 mM	0.40 mL	2.01 mL	4.03 mL
50 mM	0.08 mL	0.40 mL	0.81 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

• Kalkman β-Adrenoceptor blockade in rats enhances the ambulation induced by 5-HT_1A receptor agonists. Eur.J.Pharmacol. 1989 PMID: 2576226
• Walter Stimulant and blocking effects of optical isomers of pin. on the sinoatrial node and trachea of guinea pig. Role of β-adrenoceptor subtypes in the dissociation between blockade and stimulation. Naunyn Schmiedebergs Arch.Pharmacol. 1984 PMID: 6092972
• Corradetti Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT_1A receptors in the rat brain. Br.J.Pharmacol. 1998 PMID: 9504386

Product Documents for (S)-(-)-Pindolol