SB 204990

Catalog # Availability Size / Price Qty
4962/10
4962/50
Cat.No. 4962 - SB 204990 | C18H22Cl2O5 | CAS No. 154566-12-8
1 Image
Description: ATP citrate lyase (ACLY) inhibitor

Chemical Name: (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews (1)

Biological Activity

ATP citrate lyase (ACLY) inhibitor. Prodrug of SB 201076. Inhibits cholesterol and fatty acid synthesis in a dose-dependent manner in HepG2 cells. Orally active in vivo.

Technical Data

M.Wt:
389.27
Formula:
C18H22Cl2O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
154566-12-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline

Product Datasheets

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Citation for SB 204990

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SB-204990 were used as an ACLY inhibitor
By Anonymous on 10/05/2018
Species: Human

SB-204990 were used as an ACLY inhibitor in subconfluent endothelial cells. The images are shown in the publication PubMed ID 29429925.

PMID: 29429925

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