Scriptaid

Tocris Bioscience | Catalog # 2421

Histone deacetylase inhibitor
Tocris Bioscience
Discontinued Product
2421 has been discontinued. View all Class I Histone Deacetylases Inhibitors products.

Key Product Details

Description

Histone deacetylase inhibitor
View all Class I Histone Deacetylases Inhibitors »

Product Description

Scriptaid is a novel histone deacetylase inhibitor. Produces > 100-fold increase in histone acetylation and displays relatively low toxicity.

Product Specifications for Scriptaid

Molecular Weight

326.35

Formula

C18H18N2O4

Storage

Desiccate at -20°C

Purity

≥99% (HPLC)

Chemical Name

N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide

CAS Number

287383-59-9

PubChem ID

5186

InChI Key

JTDYUFSDZATMKU-UHFFFAOYSA-N

SMILES

ONC(=O)CCCCCN1C(=O)C2=CC=CC3=CC=CC(C1=O)=C23

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.63 100

Preparing Stock Solutions for Scriptaid

The following data is based on the product molecular weight 326.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.06 mL 15.32 mL 30.64 mL
5 mM 0.61 mL 3.06 mL 6.13 mL
10 mM 0.31 mL 1.53 mL 3.06 mL
50 mM 0.06 mL 0.31 mL 0.61 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for Scriptaid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Scriptaid

For research use only

Customer Reviews for Scriptaid (1)

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  • TGF beta high responder treated with 2 μM Scriptaid (HDAC 1/3/8 inhibitor) for 48 h. Cell lysates were analysed by western blot.
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: C3-TAg tumour cell
    Verified Customer | Posted 11/15/2019
    TGF beta high responder treated with 2 μM Scriptaid (HDAC 1/3/8 inhibitor) for 48 h. Cell lysates were analysed by western blot.
    Scriptaid 2421

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