Selexipag

Catalog # Availability Size / Price Qty
3351/10
3351/50
Cat.No. 3351 - Selexipag  | C26H32N4O4S | CAS No. 475086-01-2
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Description: Selective prostacyclin IP1 receptor agonist
Alternative Names: NS-304, ACT-293987

Chemical Name: 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide

Purity: ≥98%

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Biological Activity

Selective prostacyclin IP1 receptor agonist (Ki values are 260 and 2100 nM and for human and rat IP receptors, and >10 μM for EP1-4, DP, FP, and TP receptors). Prodrug for the active form of MRE 26. Ameliorates vascular endothelial dysfunction and increases femoral skin blood flow in rats. Orally available.

Technical Data

M.Wt:
496.62
Formula:
C26H32N4O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
475086-01-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Nippon Shinyaku Co.

Product Datasheets

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