SF 1670

Catalog # Availability Size / Price Qty
5020/10
5020/50
Cat.No. 5020 - SF 1670 | C19H17NO3 | CAS No. 345630-40-2
1 Image
Description: PTPN2 and PTEN inhibitor
Alternative Names: PTP Inhibitor XIX

Chemical Name: N-(9,10-Dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethylpropanamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

PTPN2 and PTEN inhibitor (IC50values are 0.95 and 1.78 μM, respectively). Increases fMLP-elicited PIP3 signaling, Akt -phosphorylation and production of reactive oxygen species in neutrophils in vitro. Pretreatment of transfused neutrophils enhances chemotaxis to sites of bacterial infection and increases survival in neutropenic mice. Also inhibits CD45.

Technical Data

M.Wt:
307.34
Formula:
C19H17NO3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
345630-40-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SF 1670

There are currently no reviews for this product. Be the first to review SF 1670 and earn rewards!

Have you used SF 1670?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.