Selective dopamine D1
-like receptor partial agonist (IC50
values are 19.7 and 2425 nM for binding to D1
-like and D2
-like receptors respectively). Centrally active following systemic administration in vivo
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Activation of the 5-HT1C receptor expressed in Xenopus oocytes by the benzazepines SCH 23390 and SKF 38393.
Briggs et al.
Dopamine D1 receptor family agonists, SK&F38393, SK&F77434, and SK&F82958, differentially affect locomotor activities in rats.
Meyer and Schults
Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R-(+) and S-(-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue.
Neumeyer et al.