Sorbic acid

Catalog # Availability Size / Price Qty
Sorbic acid | CAS No. 110-44-1 | DREADD Activators
1 Image
Description: Activator of hFFA2-DREADDs

Chemical Name: (2E,4E)-2,4-Hexenoic acid

Product Details

Biological Activity

Activator of hFFA2-DREADDs. Inhibits forskolin-induced cAMP production (IC50 ∼ 1 μM) and promotes accumulation of inositol monophosphates (IC50 >1 μM) in cells expressing hFFA2-DREADD. Promotes the release of GLP-1 from colonic crypts derived from hFFA2-DREADD-expressing mice.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Chemogenetics defines receptor-mediated functions of short chain free fatty acids.
    Bolognini et al.
    Nat.Chem.Biol., 2019;15:489

Product Datasheets

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