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Sorbic acid

Catalog #: 7119 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7119/100
Sorbic acid | CAS No. 110-44-1 | DREADD Activators
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Description: Activator of hFFA2-DREADDs

Chemical Name: (2E,4E)-2,4-Hexenoic acid

Purity: ≥98%

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Biological Activity

Sorbic acid is an activator of hFFA2-DREADDs. Inhibits forskolin-induced cAMP production (IC50 ∼ 1 μM) and promotes accumulation of inositol monophosphates (IC50 >1 μM) in cells expressing hFFA2-DREADD. Promotes the release of GLP-1 from colonic crypts derived from hFFA2-DREADD-expressing mice.

Technical Data

M.Wt:
112.13
Formula:
C6H8O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
110-44-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Background References

  1. Chemogenetics defines receptor-mediated functions of short chain free fatty acids.
    Bolognini et al.
    Nat.Chem.Biol., 2019;15:489

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