SP 10

Tocris Bioscience | Catalog # 7322

Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
Tocris Bioscience

Key Product Details

Description

Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
View all ACE-2 »

Product Description

SP 10 is a peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). Inhibits interaction of SARS-CoV S protein and Vero E6 cells in vitro.

Please note, this peptide displays 80% sequence identity to homologous site on SARS-CoV-2 S-protein (residues 689-697).

Product Specifications for SP 10

Molecular Weight

1315.50

Formula

C56H94N14O20S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

882157-88-2

PubChem ID

11693850

InChI Key

RBLTWUZIFRZOSV-SQWMWQRLSA-N

SMILES

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SP 10

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SP 10

For research use only

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