Potent and selective Rho-kinase inhibitor (IC50
values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.
Feng et al.
The citations listed below are publications that use Tocris products. Selected citations for SR 3677 dihydrochloride include:
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