High affinity, selective agonist of 5-HT6
values are 13, 168, and 245 nM for human 5-HT6
receptors respectively). Displays moderate affinity for human α2
adrenergic receptors (Ki
= 300 nM). Shown to increase Ca2+
concentration and phosphorylation of Fyn kinase, and regulate the activation of ERK1/2 in cloned cells.
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All Tocris products are intended for laboratory research use only.
ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned 5-HT6 receptors.
Riccioni et al.
A microdialysis study of ST1936, a novel 5-HT6 receptor agonist.
Valentini et al.
The citations listed below are publications that use Tocris products. Selected citations for ST 1936 oxalate include:
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