Chemical Name: N-(2,6-Diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
Biological ActivityST 91 is an α2-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α2 receptors over α1 receptors and acts predominantly at non-α2A-adrenoceptors which may be of the α2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats.
Takano and Yaksh
Cardiopulmonary effects of the α2-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep.
Celly et al.
Synergistic interactions between two α2-adrenoceptor agonists, dexmedetom. and ST-91, in two substrains of Sprague-Dawley rats.
Graham et al.
Citation for ST 91
The citations listed below are publications that use Tocris products. Selected citations for ST 91 include:
1 Citation: Showing 1 - 1
Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation.
Authors: Kim Et al.
Brain Res 2011;1384:110
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