ST 91

Key Product Details

Product Description

ST 91 is an α₂-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α₂ receptors over α₁ receptors and acts predominantly at non-α_2A-adrenoceptors which may be of the α_2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.

Product Specifications for ST 91

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ST 91

The following data is based on the product molecular weight 253.77.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.94 mL	19.70 mL	39.41 mL
5 mM	0.79 mL	3.94 mL	7.88 mL
10 mM	0.39 mL	1.97 mL	3.94 mL
50 mM	0.08 mL	0.39 mL	0.79 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Celly Cardiopulmonary effects of the α₂-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep. J.Pharmacol.Exp.Ther. 1999 PMID: 10215644
• Graham Synergistic interactions between two α₂-adrenoceptor agonists, dexmedetom. and ST-91, in two substrains of Sprague-Dawley rats. Pain 2000 PMID: 10692612
• Takano and Yaksh Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats. J.Pharmacol.Exp.Ther. 1992 PMID: 1349648

Product Documents for ST 91