-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α2
receptors over α1
receptors and acts predominantly at non-α2A
-adrenoceptors which may be of the α2C
subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats.
Takano and Yaksh
Synergistic interactions between two α2-adrenoceptor agonists, dexmedetomidine and ST-91, in two substrains of Sprague-Dawley rats.
Graham et al.
Cardiopulmonary effects of the α2-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep.
Celly et al.
The citations listed below are publications that use Tocris products. Selected citations for ST 91 include:
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