Swainsonine
Tocris Bioscience | Catalog # 3208
Product Description
Swainsonine is an inhibitor of α-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
Product Specifications for Swainsonine
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 8.66 | 50 |
Preparing Stock Solutions for Swainsonine
The following data is based on the product molecular weight 173.21.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 11.55 mL | 57.73 mL | 115.47 mL |
| 2.5 mM | 2.31 mL | 11.55 mL | 23.09 mL |
| 5 mM | 1.15 mL | 5.77 mL | 11.55 mL |
| 25 mM | 0.23 mL | 1.15 mL | 2.31 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.
- Olden The potential importance of swainsonine in therapy for cancers and immunology. Pharmacol.Ther. 1991 PMID: 1754603
- Sun Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine. Phytomedicine 2007 PMID: 17097281
- Tulsiani Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of golgi mannosidase II. J.Biol.Chem. 1982 PMID: 6806288
Product Documents for Swainsonine
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Swainsonine
For research use only
Citations for Swainsonine
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