Catalog Number: 3208
Chemical Name: (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
Biological Activity
Inhibitor of α-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
Technical Data
  • M.Wt:
    173.21
  • Formula:
    C8H15NO3
  • Solubility:
    Soluble to 50 mM in water
  • Storage:
    Store at -20°C
  • CAS No:
    72741-87-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of golgi mannosidase II.
    Tulsiani et al.
    J.Biol.Chem., 1982;257:7936
  2. The potential importance of swainsonine in therapy for cancers and immunology.
    Olden et al.
    Pharmacol.Ther., 1991;50:285
  3. Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine.
    Sun et al.
    Phytomedicine, 2007;14:353
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Swainsonine include:

1 Citations: Showing 1 - 1

  1. Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells.
    Authors: Tareen Et al.
    Mol Ther 2014;22:575

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