Home / Phosphodiesterase Inhibitors / TC-E 5005

TC-E 5005

4572 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4572/10
4572/50
TC-E 5005 | CAS No. 959705-64-7 | Phosphodiesterase Inhibitors
1 Image
Description: Potent and selective PDE10A inhibitor

Chemical Name: 2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine

Purity: ≥99%

Product Details
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Potent and selective PDE10A inhibitor (IC50 values are 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively and >5000 nM at PDE1B, 4A, 6, 8A and 9A). Reverses MK 801-induced hyperactivity in vivo.

Technical Data

M.Wt:
270.33
Formula:
C15H18N4O
Solubility:
Soluble to 100 mM in 1eq. HCl and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
959705-64-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TC-E 5005

Average Rating: 4 (Based on 1 Review)

5 Star
0%
4 Star
100%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used TC-E 5005?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


PDE inhibition assay in tissue culture
By Anonymous on 01/04/2018
Application: Species: Human

Dosed product into cell culture media to final concentration of 10uM and at various time points up to 72h and isolated RNA from cells for downstream qPCR analysis to review effect of PDE inhibition on cell line phenotype.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.