-hydroxysteroid dehydrogenase type 3 (17β
-HSD3) inhibitor (IC50
values are 6 and 40 nM at human and mouse 17β
-HSD3 respectively). Displays no activity at 17β
, androgen receptors or glucocorticoid receptors.
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All Tocris products are intended for laboratory research use only.
Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors.
Harada et al.