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TC-N 22A

4370 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4370/10
4370/50
TC-N 22A | CAS No. 1314140-00-5 | Group III mGluR Modulators
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Description: Potent and selective positive allosteric modulator of mGlu4 receptors

Chemical Name: 4,5,6,8-Tetrahydro-N-2-pyridinylpyrazolo[3',4':6,7]cyclohepta[1,2]thiazol-2-amine

Purity: ≥98%

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Biological Activity

TC-N 22A is a potent and selective mGlu4 receptor positive allosteric modulator (EC50 = 9 nM in human mGlu4-expressing BHK cells). Selective for mGlu4 over mGlu1, mGlu2, mGlu3, mGlu5 and mGlu7 receptors (EC50 values are > 10 μM). Brain penetrant.

Technical Data

M.Wt:
283.35
Formula:
C14H13N5S
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1314140-00-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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