Discontinued Product

3847 has been discontinued.
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Theanine | CAS No. 3081-61-6 | Glutamate Receptor Compounds
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Description: Glutamate receptor ligand

Chemical Name: N-Ethyl-L-glutamine

Product Details

Biological Activity

Amino acid analog of glutamine and component of green tea. Shown to bind to AMPA, Kainate, NMDA and group I mGlu receptors. Displays neuroprotective effects in vivo. Promotes self-renewal of human embryonic stem cells (hESC).

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
  2. Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors.
    Kakuda et al.
    Biosci.Biotechnol.Biochem., 2002;66:2683
  3. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.
    Egashira et al.
    Phytother.Res., 2008;22:65
  4. Possible involvement of group I mGluRs in neuroprotective effect of theanine.
    Nagasawa et al.
    Biochem.Biophys.Res.Comm., 2004;320:116

Product Datasheets

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