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Theanine

3847 Datasheet / COA / SDS
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3847/50
Theanine | CAS No. 3081-61-6 | Glutamate Receptor Compounds
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Description: Glutamate receptor ligand

Chemical Name: N-Ethyl-L-glutamine

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Biological Activity

Amino acid analog of glutamine and component of green tea. Shown to bind to AMPA, Kainate, NMDA and group I mGlu receptors. Displays neuroprotective effects in vivo. Promotes self-renewal of human embryonic stem cells (hESC).

Technical Data

M.Wt:
174.2
Formula:
C7H14N2O3
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
3081-61-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
  2. Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors.
    Kakuda et al.
    Biosci.Biotechnol.Biochem., 2002;66:2683
  3. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.
    Egashira et al.
    Phytother.Res., 2008;22:65
  4. Possible involvement of group I mGluRs in neuroprotective effect of theanine.
    Nagasawa et al.
    Biochem.Biophys.Res.Comm., 2004;320:116

Product Datasheets

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VersaClone cDNA Plasmids

Human GluR3 (NP_000819) VersaClone cDNA

RDC1135

Human GluR1 (NP_001107655) VersaClone cDNA

RDC1110

Human mGluR1 (AAB05337) VersaClone cDNA

RDC0983

Human GluR4 (NP_000820) VersaClone cDNA

RDC1213

Human GluR2 (NP_000817) VersaClone cDNA

RDC1113

Human mGluR5 (NP_000833) VersaClone cDNA

RDC1064

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