Catalog Number: 3847
Chemical Name: N-Ethyl-L-glutamine
Biological Activity
Amino acid analog of glutamine and component of green tea. Shown to bind to AMPA, Kainate, NMDA and group I mGlu receptors. Displays neuroprotective effects in vivo. Promotes self-renewal of human embryonic stem cells (hESC).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Desbordes SC, Placantonakis DG, Ciro A et al.
    Cell Stem Cell.
  2. Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors.
    Kakuda et al.
    Biosci.Biotechnol.Biochem., 2002;66:2683
  3. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.
    Egashira et al.
    Phytother.Res., 2008;22:65
  4. Possible involvement of group I mGluRs in neuroprotective effect of theanine.
    Nagasawa et al.
    Biochem.Biophys.Res.Comm., 2004;320:116

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