Tissue Clearing Pro

Key Product Details

Product Description

Tissue Clearing Pro is a rapid, easy-to-use, reversible and non-destructive clearing and staining kit, which allows effective tissue clearing and staining of whole tissues. Tissue Clearing Pro is a solvent based tissue clearing technique, comparable to BABB and DISCO. Tissue Clearing Pro does not cause significant shrinkage or tissue damage and does not use as harsh a solvent as other solvent based techniques.

This kit can clear a whole mouse brain of up to 8 mm thickness in 24 hours; for sections with a thickness of 1 mm this can be achieved in 2 hours. Tissue Clearing Pro is compatible with fluorescent protein, immunolabeling and small molecule staining techniques, as well as being suitable for use with all standard dyes and buffers. Following 3D imaging, Tissue Clearing Pro can be reversed for follow-up 2D histology staining. The kit comes with a getting started guide and a more comprehensive tissue clearing guidebook, providing detailed protocols. The Tissue Clearing Pro kit contains 30 mL of Tissue Clearing Pro clearing reagent 1 and 2, plus the 5 buffer solutions required to process tissues for immunolabeling, and is enough to process four whole mouse brains (approx. 2 g of tissue).

Please read the Tissue Clearing Pro Guidebook for more information and detailed protocols for using this kit.

Product Specifications for Tissue Clearing Pro

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Choi Innate lymphoid cells play a pathogenic role in pericarditis. Cell Rep. 2020 PMID: 32130902
• Regla-Nava Detection of Zika virus in mouse mammary gland and breast milk. PLoS Negl.Trop.Dis. 2019 PMID: 30742628
• Robino Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells in rhesus macaques. Bone 2020 PMID: 31972314
• Sargent Clarification and confocal imaging of the nonhuman primate placental micro-anatomy. Biotechniques 2019 PMID: 30370778

Product Documents for Tissue Clearing Pro