TLR2 Cell Lysate

Novus Biologicals | Catalog # NBP2-25060

Novus Biologicals
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Key Product Details

Species

Human

Applications

Western Blot
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Product Specifications

Application Notes

SF9 insect cells were transfected with a fusion protein containing the approximately 60 kD extracellular portion of human TLR2 and a 30 kD human Fc region. Load 20 ul/lane of a 12-well gel.

Specificity

Human TLR2/CD282 transfected cell lysate

Type

Cell

Scientific Data Images for TLR2 Cell Lysate

Western Blot: TLR2 Cell Lysate [NBP2-25060]

Western Blot: TLR2 Cell Lysate [NBP2-25060]

Western Blot: TLR2 Cell Lysate [NBP2-25060] - 20 ul of human TLR2 transfected cell lysate tested with 2 ug/ml TLR2 Antibody

Formulation, Preparation, and Storage

Formulation

1 x SDS sample buffer: 60 mM Tris-Hcl (pH 6.8) 10 mM EDTA 2 % SDS 0.03% Bromophenol Blue 10% glycerol 0.3% Beta-mercaptoethanol

Concentration

Please contact technical services for concentration.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -80C in the dark. Avoid freeze-thaw cycles.

Background: TLR2

Toll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products. The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation.

Long Name

Toll-like Receptor 2

Alternate Names

CD282

Gene Symbol

TLR2

Additional TLR2 Products

Product Documents for TLR2 Cell Lysate

Certificate of Analysis

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Product Specific Notices for TLR2 Cell Lysate

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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