Tobramycin

Tocris Bioscience | Catalog # 5390

Aminoglycoside antibiotic
Tocris Bioscience
Discontinued Product
5390 has been discontinued. View all Antibiotics products.

Key Product Details

Description

Aminoglycoside antibiotic
View all Antibiotics »

Product Description

Tobramycin is an aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H2O2.

Product Specifications for Tobramycin

Molecular Weight

467.52

Formula

C18H37N5O9

Storage

Store at +4°C

Chemical Name

O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine

CAS Number

32986-56-4

PubChem ID

36294

InChI Key

NLVFBUXFDBBNBW-PBSUHMDJSA-N

SMILES

O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 46.75 100

Preparing Stock Solutions for Tobramycin

The following data is based on the product molecular weight 467.52.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.14 mL 10.69 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL
10 mM 0.21 mL 1.07 mL 2.14 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for Tobramycin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tobramycin

For research use only

Customer Reviews for Tobramycin (1)

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  • Mechanism of action of tobramycin studied against gentamicin and neomycin m/a
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 11/30/2019
    Mechanism of action of tobramycin was studied along with other aminoglycoside antibiotics such as neomycin and gentamicin.Clinical isolate of P. aeruginosa, PAO1 (PAO1-RH) used to do susceptibility tests.
    Tobramycin 5390

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