Peptide agonist for sst1
somatostatin receptors. Somatostatin analog; inhibits tyrosine kinase activity in human colon tumor cell lines. Demonstrates an antiproliferative effect both in vitro
and in vivo
and induces apoptosis in a pancreatic tumor cell line. Does not inhibit growth hormone release or secretion.
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Evaluation of the antitumor efficacy of the somatostatin structural derivative TT-232 on different tumor models.
Tejeda et al.
Anticancer Res., 2006;26:3477
A tumor-selective somatostatin analog (TT-232) with strong in vitro and in vivo antitumor activity.
Kéri et al.
Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse.
Elekes et al.