Tyrphostin B44, (+) enantiomer

Key Product Details

Product Description

Tyrphostin B44, (+) enantiomer is an epidermal growth factor receptor (EGFR) kinase inhibitor (IC₅₀ = 0.86 μM). Slightly less active than the (-) enantiomer.

(-)-enantiomer also available.

Product Specifications for Tyrphostin B44, (+) enantiomer

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Tyrphostin B44, (+) enantiomer

The following data is based on the product molecular weight 308.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.3 mM	10.81 mL	54.05 mL	108.11 mL
1.5 mM	2.16 mL	10.81 mL	21.62 mL
3 mM	1.08 mL	5.41 mL	10.81 mL
15 mM	0.22 mL	1.08 mL	2.16 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Gazit Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 1991 PMID: 1676428

Product Documents for Tyrphostin B44, (+) enantiomer