; can be used as a negative control. Inhibits Panx1 currents in HEK cells. Also inhibits vasopressin- and GTP
influx in hepatocytes.
Active Analog also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell.
Muto et al.
Activation of P2X 7 receptors induces CCL3 production in microglial cells through transcription factor NFAT.
Kataoka et al.
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells.
Ma et al.
Evidence obtained using single hepatocytes for inhibition by the phospholipase C inhibitor U73122 of store-operated Ca 2+ inflow.
Berven and Barritt
The citations listed below are publications that use Tocris products. Selected citations for U 73343 include:
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