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U 89843A

   
Product Datasheet
Catalog Number:2734
Alternate Names:PNU 89843
Chemical Name:6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine hydrochloride
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Biological Activity
Positive allosteric modulator of GABAA receptors. Enhances GABA-induced Cl- currents in the α1β2γ2, α3β2γ2 and α6β2γ2 subtypes. Causes sedation in vivo following i.v. administration without losing "righting reflex". Also displays antioxidant activity.
Technical Data
  • M.Wt:
    321.85
  • Formula:
    C16H23N5.HCl
  • Solubility:
    Soluble to 25 mM in water and to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    157013-85-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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