UBP1112

Key Product Details

Product Description

UBP1112 is an a selective group III mGlu receptor antagonist (apparent K_d values are 5.1 and 488 μM for group III and group II mGlu receptors respectively; IC₅₀ > 1 mM for group I, NMDA, AMPA and kainate receptors).

Product Specifications for UBP1112

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for UBP1112

The following data is based on the product molecular weight 259.20.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.86 mL	19.29 mL	38.58 mL
5 mM	0.77 mL	3.86 mL	7.72 mL
10 mM	0.39 mL	1.93 mL	3.86 mL
50 mM	0.08 mL	0.39 mL	0.77 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

• Miller Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. Br.J.Pharmacol. 2003 PMID: 12922940
• Conway Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors. Bioorg.Med.Chem.Lett. 2001 PMID: 11277518

Product Documents for UBP1112