UNC 1215

   
Product Datasheet
Catalog Number:4666
Chemical Name:2-Phenylamino-1,4-[4-(pyrrolidinyl)piperidinyl)benzamide
Product Details
Reviews
Biological Activity
Potent inhibitor of L3MBTL3 methyllysine (Kme) reader domain (IC50 = 40 nM; Kd = 120 nM). Displays >100-fold selectivity over a panel of histone methyltransferases, kinases, ion channels and 7-TM receptors. Disrupts subnuclear localization and foci formation of fluorescently-labeled L3MBTL3 in HEK293 cells.
External Portal Information
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of UNC 1215 is reviewed on the chemical probes website.
Technical Data
  • M.Wt:
    529.72
  • Formula:
    C32H43N5O2
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in 2eq.HCl
  • Purity:
    >99
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the UNC 1215 probe summary on the SGC website.
Product Datasheets

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