Catalog Number: 4516
Chemical Name: (3-Bromophenyl)[4-(1-prrolidinyl)-1-piperidinyl]methanone hydrochloride
Biological Activity
Methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.
Technical Data
  • M.Wt:
    373.72
  • Formula:
    C16H21BrN2O.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    1184136-10-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-activity relationships of methyl-lysine reader antagonists.
    Herold et al.
    Med.Chem.Comm, 2012;3:45

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