URI Antibody

Novus Biologicals | Catalog # NB100-59778

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all URI Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 458 and 508 of human RNA polymerase II, subunit 5 (RPB5)-mediating protein using the numbering given in entry BAA34781.1 (GeneID 8725).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for URI Antibody

Western Blot: URI Antibody [NB100-59778]

Western Blot: URI Antibody [NB100-59778]

Western Blot: URI Antibody [NB100-59778] - Detection of Human RMP on HeLa whole cell lysate (5, 15, and 50 microgram) and 293T (50 microgram) using NB100-59778. RMP was also immunoprecipitated by rabbit anti-RMP antibody NB100-59777.

Applications for URI Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: URI

RMP [RNA polymerase II subunit 5(RPB5)-mediating protein] interacts with RPB5 to negatively regulate RNA polymerase II transcription. RMP has corepressor activity that is facilitated by its association with DMAP1 (DNA methyltransferase 1-associating protein). RMP appears to be involved in mTOR kinase signaling.

Alternate Names

chromosome 19 open reading frame 2, FLJ10575, NNX3RPB5-mediating protein, Protein NNX3, RMPunconventional prefoldin RPB5 interactor, RNA polymerase II subunit 5-mediating protein, URIRNA polymerase II, subunit 5-mediating protein

Entrez Gene IDs

8725 (Human)

Gene Symbol

URI1

UniProt

BAA34781.1 (Human)

Additional URI Products

Product Documents for URI Antibody

Certificate of Analysis

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Product Specific Notices for URI Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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