Inhibitor of acetylcholine transport (Ki
= 2 nM). Centrally active following systemic administration in vivo
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All Tocris products are intended for laboratory research use only.
N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters.
Efange et al.
Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats.
Kobayashi et al.
Brain Res.Bull., 1997;43:17
Active transport of acetylcholine by the human vesicular acetylcholine transporter.
Varoqui and Erickson