VprBP Antibody

Name: VprBP Antibody
Brand: Novus Biologicals
SKU: NBP1-05953
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-05953

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1457 and 1507 of human Vpr (HIV-1) binding protein using the numbering given in entry NP_055518.1 (GeneID 9730).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VprBP Antibody

Western Blot: VprBP Antibody [NBP1-05953]

Western Blot: VprBP Antibody [NBP1-05953] - Whole cell lysate from HeLa and 293T (T; 50 ug) cells. VprBP was also immunoprecipitated by another rabbit anti-VPRBP antibody NBP1-05952.

Applications for VprBP Antibody

Application

Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: VprBP

VprBP (HIV-1 Vpr-binding protein) is also known as DCAF1 (Ddb1- and Cul4-associated factor 1). VprBP was initially identified as a protein that co-immunoprecipitated with the HIV protein, viral protein R; however the physiological relevance of this association remains unclear. It has recently been shown that VprBP plays an essential role in cell cycle progression, and it associates with the DDB1-CUL4 E3 ligase complex. Alternate names for VprBP include Vpr-interacting protein, RIP, and KIAA0800.

Alternate Names

DCAF1DDB1 and CUL4 associated factor 1, DDB1- and CUL4-associated factor 1, HIV-1 Vpr-binding protein, KIAA0800protein VPRBP, MGC102804, RIP, Vpr (HIV-1) binding protein, Vpr-binding protein, VprBP, Vpr-interacting protein

Entrez Gene IDs

9730 (Human)

Gene Symbol

DCAF1

UniProt

Q9Y4B6 (Human)

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Product Documents for VprBP Antibody

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Certificate of Analysis

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Product Specific Notices for VprBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for VprBP Antibody

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