W-13 hydrochloride

Tocris Bioscience | Catalog # 0361

Calmodulin antagonist
Tocris Bioscience
Discontinued Product
0361 has been discontinued. View all Calcium Binding Protein Modulator Antagonists products.

Key Product Details

Description

Calmodulin antagonist
View all Calcium Binding Protein Modulator Antagonists »

Product Description

W-13 hydrochloride is a calmodulin antagonist (inhibits calmodulin activated PDE activity with an IC50 of 68 μM). Inhibits growth of tamoxifen-resistant breast cancer cells.

Product Specifications for W-13 hydrochloride

Molecular Weight

349.27

Formula

C14H17ClN2O2S.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride

CAS Number

88519-57-7

PubChem ID

16760706

InChI Key

QKAALLVQBOLELJ-UHFFFAOYSA-N

SMILES

Cl.NCCCCNS(=O)(=O)C1=CC=C2C(Cl)=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 34.93 100
DMSO 34.93 100

Preparing Stock Solutions for W-13 hydrochloride

The following data is based on the product molecular weight 349.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.86 mL 14.32 mL 28.63 mL
5 mM 0.57 mL 2.86 mL 5.73 mL
10 mM 0.29 mL 1.43 mL 2.86 mL
50 mM 0.06 mL 0.29 mL 0.57 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for W-13 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for W-13 hydrochloride

For research use only

Citations for W-13 hydrochloride

Customer Reviews for W-13 hydrochloride (1)

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  • PN and PH cells were treated with W-7 (catalog no. 0369) and W-13 (catalog no. 0361) purchased from Tocris.
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: PN and PH cells
    Verified Customer | Posted 11/17/2019
    PN and PH cells were treated with W-7 (catalog no. 0369) and W-13 (catalog no. 0361) purchased from Tocris.
    W-13 hydrochloride 0361

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