W-5 hydrochloride

Key Product Details

Product Description

W-5 hydrochloride is a calmodulin antagonist (inhibits Ca²⁺-calmodulin dependent PDE with an IC₅₀ of 240 μM).

Product Specifications for W-5 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for W-5 hydrochloride

The following data is based on the product molecular weight 342.88.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.83 mL	29.16 mL	58.33 mL
2.5 mM	1.17 mL	5.83 mL	11.67 mL
5 mM	0.58 mL	2.92 mL	5.83 mL
25 mM	0.12 mL	0.58 mL	1.17 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Hidaka N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 1981 PMID: 6945588
• Hidaka and Tanaka Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 1983 PMID: 6139736
• Hidaka Activity-structure relationship of calmodulin antagonists. Naphthalenesulfonamide derivatives. Mol.Pharmacol. 1981 PMID: 7329399

Product Documents for W-5 hydrochloride