Y-25130 hydrochloride

Tocris Bioscience | Catalog # 0380

Potent and selective 5-HT3 antagonist
Tocris Bioscience
Discontinued Product
0380 has been discontinued. View all 5-HT3 Receptor Antagonists products.

Key Product Details

Description

Potent and selective 5-HT3 antagonist
View all 5-HT3 Receptor Antagonists »

Product Description

Y-25130 hydrochloride is a selective and potent 5-HT3 antagonist (Ki = 2.9 nM).

Product Specifications for Y-25130 hydrochloride

Molecular Weight

386.28

Formula

C17H20ClN3O3.HCl

Storage

Desiccate at -20°C

Purity

≥99% (HPLC)

Chemical Name

N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide hydrochloride

CAS Number

123040-16-4

PubChem ID

115000

InChI Key

DBMKBKPJYAHLQP-UHFFFAOYSA-N

SMILES

Cl.CN1C(=O)COC2=C(C=C(Cl)C=C12)C(=O)NC1CN2CCC1CC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100
DMSO 3.86 10

Preparing Stock Solutions for Y-25130 hydrochloride

The following data is based on the product molecular weight 386.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.59 mL 12.94 mL 25.89 mL
5 mM 0.52 mL 2.59 mL 5.18 mL
10 mM 0.26 mL 1.29 mL 2.59 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for Y-25130 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Y-25130 hydrochloride

For research use only

Citations for Y-25130 hydrochloride

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