Z-Leu-Leu-Glu-AMC (Z-LLE-AMC)

Catalog # Availability Size / Price Qty
S-230-05M
Product Details
Citations (9)
FAQs
Reviews (1)

Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-Species

Product Datasheets

Citations for Z-Leu-Leu-Glu-AMC (Z-LLE-AMC)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

9 Citations: Showing 1 - 9
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  1. Pre-Clinical Evaluation of the Proteasome Inhibitor Ixazomib against Bortezomib-Resistant Leukemia Cells and Primary Acute Leukemia Cells
    Authors: MSF Roeten, J van Meerlo, ZJ Kwidama, G Ter Huizen, WH Segerink, S Zweegman, GJL Kaspers, G Jansen, J Cloos
    Cells, 2021;10(3):.  2021
  2. Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition
    Authors: T Hirano, N Suzuki, Y Ikenaka, N Hoshi, Y Tabuchi
    Toxicology and Applied Pharmacology, 2021;430(0):115723.  2021
  3. NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
    Authors: L Brandolini, A Antonosant, C Giorgio, M Bagnasco, M d'Angelo, V Castelli, E Benedetti, A Cimini, M Allegretti
    Sci Rep, 2020;10(1):18337.  2020
  4. Diurnal Rhythms Spatially and Temporally Organize Autophagy
    Authors: M Ryzhikov, A Ehlers, D Steinberg, W Xie, E Oberlander, S Brown, PE Gilmore, RR Townsend, WS Lane, T Dolinay, K Nakahira, AMK Choi, JA Haspel
    Cell Rep, 2019;26(7):1880-1892.e6.  2019
  5. A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth
    Authors: X Li, Q Huang, H Long, P Zhang, H Su, J Liu
    EBioMedicine, 2018;0(0):.  2018
  6. YOD1 attenuates neurogenic proteotoxicity through its deubiquitinating activity
    Authors: K Tanji, F Mori, Y Miki, J Utsumi, H Sasaki, A Kakita, H Takahashi, K Wakabayash
    Neurobiol. Dis., 2018;112(0):14-23.  2018
  7. Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation
    Authors: X Lan, C Zhao, X Chen, P Zhang, D Zang, J Wu, J Chen, H Long, L Yang, H Huang, X Wang, X Shi, J Liu
    Cell Death Dis, 2017;8(7):e2913.  2017
  8. Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum
    Authors: M Ye, H Qiu, Y Cao, M Zhang, Y Mi
    Front. Pharmacol, 2017;8(0):148.  2017
  9. Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study
    Sci Rep, 2016;6(0):33444.  2016

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Reviews for Z-Leu-Leu-Glu-AMC (Z-LLE-AMC)

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Z-Leu-Leu-Glu-AMC (Z-LLE-AMC)
By Anonymous on 05/02/2020
Application:

S-230 hydrolysis confirmation by LCMS-SRM
S-230: 1 uM
i20S: 15 nM
PA28a: 150 nM
Reaction: 37 °C for 5 h
1:S-230 Z-LLE-AMC (665.25>490.15)
2:Free AMC (176.25>120.00)
3:S-230 Z-LLE-COOH (508.25>361.15)