ZK 93423 hydrochloride

   
Product Datasheet
Catalog Number:1994
Chemical Name:4-(Methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester hydrochloride
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Biological Activity
Potent benzodiazepine receptor agonist (IC50 = 1 nM). Non-selective between α1-, α2-, α3- and α5-subunit containing GABAA receptors (Ki values are 4.1, 4.2, 6 and 4.5 nM for inhibition of [3H]Ro15-1788 binding to human recombinant α1β3γ2, α2β3γ2, α3β3γ2 and α5β3γ2 receptors respectively). Anxiolytic following systemic administration in vivo.
Technical Data
  • M.Wt:
    426.9
  • Formula:
    C23H22N2O4.HCl
  • Solubility:
    Soluble to 30 mM in DMSO and to 5 mM in ethanol
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    1216574-52-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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