ZQ 16

  ( 1 citations )    
Product Datasheet
Catalog Number:6001
Chemical Name:2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
Product Details
Citations (1)
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Reviews
Biological Activity
Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro.
Technical Data
  • M.Wt:
    228.31
  • Formula:
    C10H16N2O2S
  • Solubility:
    Soluble to 50 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    376616-73-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ZQ 16 include:

1 Citations: Showing 1 - 1

  1. Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R.
    Authors: Sundqvist
    Biochim Biophys Acta  2018;1865(5):695

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