Webinar: From Organoids to Assembloids: Building Better Models of Human Disease
Webinar Summary
Standard organoid cultures have transformed disease research — but they still struggle to capture the multi-cell-type architecture that drives disease progression in vivo.
What You’ll Learn
Hear directly from Prof. Hans Clevers, the pioneer who built the field of organoid biology from the first Lgr5+ stem cell–derived mini-guts. This webinar bridges the gap between basic organoid culture and the CRISPR-editable, drug-screening-ready systems now making real disease modeling possible.
Key Takeaways
- How adult stem cell-derived organoids enable long-term tissue expansion, gene editing with CRISPR/Cas9, and personalized drug screening
- How Lgr5 was identified as a specific marker for active epithelial stem cells beyond the intestine — including hair follicles, kidney, liver, mammary gland, inner ear, tongue, and stomach epithelium
- How single sorted stem cells can initiate ever-expanding “mini-gut” organoids in 3D culture, opening new possibilities for personalized medicine and gene therapy
- Practical frameworks for increasing organoid complexity without sacrificing reproducibility
Who Should Watch
Researchers in stem cell biology, disease modeling, tissue engineering, drug development, or regenerative medicine who want to move beyond simple organoids should view this webinar.
Or visit our organoids page to learn more about R&D Systems organoid solutions.
Speakers
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Prof. Hans Clevers, MD, PhD |
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Didarul Bhuiyan, PhD |