Adrenergic beta 2 Receptor Inverse Agonists Small Molecules and Peptides

The adrenergic β₂ receptor (β₂-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes α_1A, α_1B, α_1D, α_2A, α_2B, α_2C, β₁ and β₃. They are located primarily in the CNS, heart, kidney and muscle where they are involved in smooth muscle relaxation (e.g. bronchodilation). The human adrenergic β₂ receptor gene has been localized to chromosome 5 (5q31-q32)