5 results for "ALK-7 Small Molecules and Peptides" in Products

ALK-7 Small Molecules and Peptides

ALKs 1-7 are type I serine/threonine kinase receptors for TGF-beta superfamily members. They undergo hetero-oligomerization with type II serine/threonine kinase receptors to transduce signals, usually through Smad proteins. Alk-1 binds TGF-beta and Alk-7 is thought to bind nodal.

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)
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SB 431542 synthesized to cGMP guidelines

Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
SB 431542 synthesized to cGMP guidelines
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Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(6)
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Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine
Purity: ≥98%
Selective inhibitor of TGF-βRI, ALK4 and ALK7
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Potent TGF-βRI inhibitor

Chemical Name: 4-[[4-[(2.6-Dimethyl-3-pyridinyl)oxy]-2-pyridinyl]amino]benzenesulfonamide
Purity: ≥98%
Potent TGF-βRI inhibitor
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