SB 505124

Catalog # Availability Size / Price Qty
3263/10
3263/50
SB 505124 | CAS No. 694433-59-5 | TGF-beta Receptor Inhibitors
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Description: Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine

Purity: ≥98%

Product Details
Citations (5)
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Biological Activity

Selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively). Selectively inhibits signaling from TGF-β and activin; does not inhibit other ALK family members.

Technical Data

M.Wt:
335.4
Formula:
C20H21N3O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
694433-59-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for SB 505124

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