Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
1 result for "alpha-1A Adrenergic R/ADRA1A" in Products
alpha-1A Adrenergic R/ADRA1A Products
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G proteins. These various subtypes show different patterns of activation. ADRA1A encodes the alpha-1A-adrenergic receptor. ADRA1A is expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary.
Selective α1A adrenergic receptor Degrader (PROTAC®)
| Chemical Name: | 2-(2-(2-(2-(4-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide |
| Purity: | ≥98% |
Loading...