BAP1 Proteins and Enzymes

Breast Cancer 1 (BRCA1) Associated Protein-1 (BAP1) is a deubiquitinating enzyme that was identified in a screen for proteins that interact with BRCA1. The human protein has a predicted molecular weight of 81 kDa and shares 93% and 92% amino acid (aa) sequence identity with the mouse and rat orthologs, respectively. BAP1 has two functional domains,...